Core Needle Biopsy

At Thyroid Medical Institute, we offer Core Needle Biopsy, an advanced diagnostic procedure used to obtain precise tissue samples from thyroid nodules or neck masses. This minimally invasive test delivers clearer results than fine-needle aspiration in complex cases, helping guide confident treatment decisions.

Led by Dr. Rodolfo A. Perez, a board-certified endocrinologist with over 30 years of specialized experience, our team prioritizes your comfort, safety, and understanding from consultation through recovery.

What Is a Core Needle Biopsy?

A Core Needle Biopsy uses a larger gauge needle to extract a small cylinder of whole tissue rather than just cells. This provides:

  • Clearer architectural detail—the tissue’s structure can be neatly examined
  • More conclusive results, especially when previous testing was inconclusive

It is often recommended when a fine-needle aspiration (FNA) biopsy doesn’t provide sufficient information—or when a deeper tissue sample is needed to guide treatment.

When Is Core Needle Biopsy Recommended?

Dr. Perez may suggest this procedure if:

  • An FNA biopsy returned indeterminate or inconclusive results

  • Imaging shows complex or suspicious features like calcifications, irregular nodule shape, or firm texture

  • You have a history of thyroid cancer or a high risk for malignancy

  • Previous biopsies haven’t matched imaging findings or symptoms

  • Accurate tissue architecture is required to guide surgical or medical decisions

In these cases, core needle biopsy offers greater diagnostic confidence—potentially avoiding unnecessary surgery or enabling timely intervention.

What to Expect During the Procedure

With Core Needle Biopsy, our goal is to combine diagnostic precision with patient comfort.

  1. Pre‑procedure consultation
     Dr. Perez will review your medical history, imaging, and prior biopsy results. He’ll explain the need for a core biopsy and answer any questions.

  2. Ultrasound guidance
     The procedure is performed under real‑time ultrasound to precisely target the nodule or lesion.

  3. Anesthesia
     A local anesthetic is applied to numb the area, ensuring minimal discomfort.

  4. Tissue sampling
     A small incision is made, and a hollow core needle is gently inserted into the nodule. One or more small cylinders of tissue are removed.

Minimal downtime
 A sterile adhesive bandage is applied; no stitches are needed. The entire process typically takes 30 to 45 minutes.

Is It Painful?

Most patients describe the procedure as simply uncomfortable, not painful—saying they feel pressure or mild pushing. The local anesthetic effectively blocks significant sensation, and recovery is usually quick:

  • Minor cramping or bruising is common and typically resolves within a few days

  • Most people resume regular activities immediately afterward

We stay with you through the process to address any concerns and ensure your comfort throughout.

After the Biopsy

Core needle biopsy results can take 5–7 days, sometimes longer if detailed pathological analysis is required. During this time:

  • Avoid vigorous activity for 24 hours

  • Apply ice to reduce swelling if needed

  • Watch for side effects (which are rare): pain, bleeding, or infection

Arrangements will be made for post‑procedure follow-up:

  • Dr. Perez will review results personally, explaining tissue structure and whether it is benign, malignant, or atypical

  • Based on the findings, he will work with you to form a clear care plan—whether that’s monitoring, additional testing, surgery, or medical therapy

In most cases, core needle biopsy provides a clear diagnosis—including detecting rarer cancers or complex pathologies that FNA misses.

Benefits of In‑House Core Needle Biopsy

Performing this advanced procedure in‑office at Thyroid Medical Institute allows you to:

  • Receive integrated care from diagnosis through definitive treatment

  • Avoid multiple referrals and long waits

  • Benefit from fast scheduling and prompt results

  • Have a consistent care team—Dr. Perez reviews imaging, guides the procedure, and explains results

This streamlined approach ensures clarity, speed, and compassionate support every step of the way.

Schedule Your Core Needle Biopsy Consultation

If your thyroid evaluation requires a more detailed tissue sample than FNA can provide, a Core Needle Biopsy may be the best next step. This procedure often results in fewer repeat biopsies, avoids unnecessary surgery, and enables confident treatment decisions.

📞 Call (305) 512-4411 or book your consultation online today to schedule your Core Needle Biopsy with Thyroid Medical Institute.


 Let precision guide your care—trust our expertise to clarify your thyroid health.